Oligodendrocytes: Myelination and Axonal Support
نویسندگان
چکیده
منابع مشابه
NGF Controls Axonal Receptivity to Myelination by Schwann Cells or Oligodendrocytes
Axons dictate whether or not they will become myelinated in both the central and peripheral nervous systems by providing signals that direct the development of myelinating glia. Here we identify the neurotrophin nerve growth factor (NGF) as a potent regulator of the axonal signals that control myelination of TrkA-expressing dorsal root ganglion neurons (DRGs). Unexpectedly, these NGF-regulated ...
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Acknowledgements First I would like to acknowledge my lab mates Allison Vestaal-Laborde, Andrew Eschenroder and Manisha Magar, without whom I would have been lost in my journey through the creation of this thesis. More importantly they were always incredibly good at keeping me laughing through all the pitfalls encountered in gathering my data and trying to put it to paper. giving me guidance an...
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Neuregulins comprise a family of epidermal growth factor-like ligands that interact with ErbB receptor tyrosine kinases to control many aspects of neural development. One of the most dramatic effects of neuregulin-1 is on glial cell differentiation. The membrane-bound neuregulin-1 type III isoform is an axonal ligand for glial ErbB receptors that regulates the early Schwann cell lineage, includ...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Perspectives in Biology
سال: 2015
ISSN: 1943-0264
DOI: 10.1101/cshperspect.a020479